Publications

Learning anisotropic interaction rules from individual trajectories in a heterogeneous cellular population
Our applied math collaborators use my motility data to help them understand how and why cells move in populations with more than one cell type.
Daniel A. Messenger, Graycen Wheeler, Xuedong Liu, David M. Bortz
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Protocol for analysis and consolidation of TrackMate outputs for measuring two-dimensional cell motility using nuclear tracking
Does what it says on the tin.
Graycen Wheeler, Amrita Purkayastha, Eric N. Bunker, David M. Bortz, Xuedong Liu
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Genome-wide binding analysis of 195 DNA binding proteins reveals “reservoir” promoters and human specific SVA-repeat family regulation
Re-analyzed ENCODE data reveal 1,362 ‘reservoir’ promoters with up to 111 different DNA-binding proteins present but no steady-state RNA expression.
Michael J. Smallegan, Soraya Shehata, Savannah F. Spradlin, Alison Swearingen, Graycen Wheeler, Arpan Das, Giulia Corbet, Benjamin Nebenfuehr, Daniel Ahrens, Devin Tauber, Shelby Lennon, Kevin Choi, Thao Huynh, Tom Wieser, Kristen Schneider, Michael Bradshaw, Joel Basken, Maria Lai, Timothy Read, Matt Hynes-Grace, Dan Timmons, Jon Demasi, John L. Rinn
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Suppression of alpha-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-alpha autocrine/paracrine signaling
Perturbation of adherens junctions elevates autocrine TGF-α signaling via membrane-bound protease TACE, which sustains elevated proliferation and motility in keratinocytes.
Eric N. Bunker, Graycen Wheeler, Douglas A. Chapnick, Xuedong Liu
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Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers
Histone deacetylase inhibitors prefererentially suppress expression super-enhancer-driven genes, which are associated with cancer.
Gilson A. Sanchez, Phillip A. Richmond, Eric N. Bunker, Samuel S. Karman, Joseph Azofeifa, Aaron T. Garnett, Quanbin Xu, Graycen Wheeler, Cathryn Toomey, Qinghong Zhang, Robin D. Dowell, Xuedong Liu
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