Perturbation of adherens junctions elevates autocrine TGF-α signaling via TACE. Graycen and Eric are co-first authors on this paper, which is in press at Molecular Biology of the Cell.
Re-analyzed ENCODE data reveal 1,362 'reservoir' promoters with up to 111 different DNA-binding proteins present but no steady-state RNA expression.
A poster presentation for the American Society for Biochemistry & Molecular Biology Experimental Biology meeting on my contribution to Sanchez et al. (2018).
Histone deacetylase inhibitors prefererentially suppress expression super-enhancer-driven genes, which are associated with cancer.