serious work

Suppression of alpha-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-alpha autocrine/paracrine signaling

Perturbation of adherens junctions elevates autocrine TGF-α signaling via TACE. Graycen and Eric are co-first authors on this paper, which is in press at Molecular Biology of the Cell.

Genome-wide binding analysis of 195 DNA-binding proteins reveals reservoir promoters and human-specific SVA family repeat region

Re-analyzed ENCODE data reveal 1,362 'reservoir' promoters with up to 111 different DNA-binding proteins present but no steady-state RNA expression.

Histone deacetylase inhibition leads to dose-dependent suppression of oncogene-associated super-enhancers

A poster presentation for the American Society for Biochemistry & Molecular Biology Experimental Biology meeting on my contribution to Sanchez et al. (2018).

Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers

Histone deacetylase inhibitors prefererentially suppress expression super-enhancer-driven genes, which are associated with cancer.